21 Best Celebrity Cameos on Friends

Brad Pitt

How could we forget Pitt (then married to Jennifer Aniston), who played Will, co-founder of "The I Hate Rachel Green Club"?

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George Clooney and Noah Wyle

The worlds of mid-'90s NBC heavy hitters collided when ER stars Clooney and Wyle showed up—in scrubs!—as the cute doctors treating Rachel's ankle.

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Julia Roberts

Roberts played Chandler's former classmate, Susie Moss (aka "Susie Underpants"), whom he humiliated in the fourth grade. Jean-Claude Van Damme also guest starred in the same episode.

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Winona Ryder

Back in the early aughts, Winona Ryder made her appearance on the show as Melissa Warburton, Rachel's old college friend she kissed after a wild, sangria-fueled night of partying. Melissa pretended not to remember that encounter — until a kiss from Rachel to prove it happened elicits a long-held love confession.

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Bruce Willis

Rachel dated Paul Stevens (Willis), the dad of a student Ross is seeing.

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Anna Faris

Faris guest starred as the pregnant mother whose twins Monica and Chandler end up adopting.

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Reese Witherspoon

Rachel's younger sister Jill (a baby-faced Witherspoon) comes into town and goes on a date with Ross.

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Ben Stiller

Rachel's date Tommy (Stiller) CAN'T STOP SCREAMING.

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Brooke Shields

Joey went on a date with Erika Ford (Shields), a fan who believed he was actually Dr. Drake Ramoray — and quickly revealed her stalker tendencies.

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Susan Sarandon

Joey got a chance to rejoin Days of Our Lives when his comatose character receives the brain of castmate Jessica Lockhart (Sarandon), who he ends up sleeping with off-screen.

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Aisha Tyler

Tyler played Charlie, a professor who starts off dating Joey before becoming the love interest of fellow paleontologist Ross.

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Tom Selleck

The famous mustachioed Selleck played Monica's on-again, off-again boyfriend, Dr. Richard Burke.

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Christine Taylor

Taylor played Bonnie, Ross's girlfriend, who shaves her head at Rachel's urging.

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Dakota Fanning

Mackenzie (Fanning), the 8-year-old who is moving out of the house Monica and Chandler are buying, offers consolation to a saddened Joey.

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Charlton Heston

The inimitable actor played himself, sharing his pearls of wisdom with Joey.

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Kristin Davis

Rachel and Phoebe found the perfect girl for Joey in Erin (Davis), but he doesn't return her affections.

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Billy Crystal and Robin Williams

The legendary comics cozied up on the famous Central Perk couch and shared a "private" conversation that had the rest of the friends all ears.

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Sean Penn

Phoebe gave Ursula's fiancé Eric (Penn) the truth about her twin sister.

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Helen Hunt

In another guest cameo by a fellow NBC star, Mad About You's Hunt played Jamie, a customer of Phoebe's twin sister Ursula, the always-confused waitress at their usual haunt.

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