The 16 Best Clinical Strength Deodorants, Tested & Reviewed

Best Overall

Uriage Clinical Strength Deodorant

View On Amazon $14 View On Uriage.com $14 View On IHerb $14

Designed to last for 24 hours, Uriage Clinical Strength Deodorant has made waves for its fresh, long-lasting appeal. It doubles as an antiperspirant, meaning it blocks odor, as well as sweat. While our tester admittedly found that it doesn’t last in its full glory for 24 hours, they were amazed by the product's performance nonetheless. “The deodorant went on smoothly and was instantly absorbed — it wasn’t tacky, sticky, or greasy, and left no stains on the black shirt that I wore,” they say. “I used it as directed, and even though I had minor sweat, no odor permeated through my clothes, and it still smelled and felt good."

Other highlights of this top-rated deo? It’s hypoallergenic, has a fresh unisex scent, and it’s infused with Uriage Thermal Water to nourish under-arm skin — all for under $15.

Type: Roll-on | Scent: Fresh | Lasting power: ~24 hours | Antiperspirant: Yes

Best Budget

Certain Dri Clinical Prescription Strength Antiperspirant

View On Amazon $6 View On Riteaid.com $8 View On Herbspro.com

Considering the name of this deodorant, you might be surprised to find that it applies wet — our tester was. That said, once on, Certain Dri Clinical Prescription Strength Antiperspirant dries down to a matte finish that offers full coverage against odor and sweat, without leaving any residue on clothes in the process.

“The deodorant neutralized any odor, but didn't have any noticeable fragrance either,” our tester reveals. “I felt coverage spanned over 24 hours — odor only started creeping in just after 24 hours, and [my full-fledged] natural body odor [only became noticeable] after a rigorous day of work the second day.”

While the deo performs well, feels comfortable, and doesn’t transfer, our tester admits that it has a slightly chalky feel, which they imagine would become more noticeable with more than two swipes of the product. Still, given the performance and the price, they found it was impossible to beat.

Type: Roll-on | Scent: Unscented | Lasting power: 24+ hours | Antiperspirant: Yes

Best Splurge

Donna Karan Cashmere Mist Deodorant

View On Amazon $32 View On Nordstrom $32 View On Nordstrom $32

Donna Karan Cashmere Mist Deodorant is beloved by over 35,000 Sephora shoppers — and for good reason. Unlike most deodorants, this deo is designed to smell like a luxury perfume. “This scent is very unique; it’s definitely the best-smelling deodorant I've ever experienced,” our tester reveals.

Scent aside, we found the deodorant, which is an antiperspirant stick, performs well, too. “The consistency of the product is very light, almost powdery,” our tester says, marveling over just how smoothly it applies. While it doesn’t block against odor and sweat all day long, it does adequately provide coverage for 12 to 16 hours. The one downside is that it leaves a slight-but-noticeable white residue. “There was a tiny, tiny amount of white on my t-shirt, but not much to bother me,” our tester admits.

Type: Stick | Scent: Cashmere | Lasting power: 12 hours | Antiperspirant: Yes

Best Antiperspirant

Secret Antiperspirant Deodorant with Pure Essential Oils

View On Amazon $10 View On Walmart $11

Secret Antiperspirant Deodorant for Women With Pure Essential Oils smells deliciously of coconut and mandarin — which our tester found to be one of three key highlights of the product. “The scent was really lovely; it smelled fresh and clean, without being too perfumey or overpowering,” they say. “If they made a candle version of it, I would burn it in my room all day long.”

Another key takeaway? It’s an incredible antiperspirant — in fact, the best of the bunch. “After completing a 15-minute brisk walk on the treadmill, I had worked up a sweat on my forehead and neck, but didn't feel much, if any, dampness on my armpits — this deodorant is very effective,” our tester says. “Over the course of 24 hours, my armpit would get slightly damp when I was active (walking outside in the heat, packing for my move, etc.), but not enough to make my shirt sleeve wet. The antiperspirant effects are impressive.”

From a transfer stance, this deo wowed us even further. “Because of the standard dry, white form of deodorant, I expected there to be a significant white mark on the inside of my t-shirt, but I had to really look to find one minor white dot,” our tester says. “I was pleasantly surprised by the lack of transfer.”

The only downside was the consistency. “It didn’t glide smoothly onto my armpits, as it was slightly dry,” our tester says. “But it wasn't sticky or greasy — it had a barely-there feeling, which I found comfortable [once applied].”

Type: Stick | Scent: Coconut Oil + Mandarin | Lasting power: 24 hours | Antiperspirant: Yes

Best for Sensitive Skin

Vanicream Anti-Perspirant Deodorant

View On Amazon $66 View On Herbspro.com View On Carewell.com

If you have sensitive skin, this fragrance-free antiperspirant deodorant is a must. Beloved by over 10,000 Amazon shoppers, Vanicream Anti-Perspirant Deodorant works well to block everyday sweat and odor — as in the type you’d experience going about your commute, running errands, engaging in a low-to-moderate intensity workout, and so on. “In 24 hours, I did a brisk walking workout, had a very hot and sweaty commute home, and did a second low-intensity strength training workout — I'm pretty impressed that there is no odor,” our tester reveals.

While it works well to block sweat and provide odor protection, this stick deodorant does leave behind white residue. “This product doesn't claim to go on clear. It did leave some white residue on my shirt after a workout, but it washes out easily and doesn't result in any staining,” our reviewer says.

That’s not enough to be a deterrent, though. “I really love that this deodorant doesn't have any fragrance at all. And since I went the full 24-hour period (with a few workouts and a very sweaty commute) without noticing any smells, I'd say it doesn't need any added fragrance to work.”

Type: Stick | Scent: Unscented | Lasting power: 24 hours | Antiperspirant: Yes

Best Unscented

DERMAdoctor Total Nonscents Ultra Gentle Antiperspirant

View On Amazon $25 View On Skincarerx.com View On Macy's $25

DERMAdoctor Total Nonscents Ultra Gentle Antiperspirant is another fabulous option for sensitive skin, not to mention our top pick as far as unscented formulas go. “I have very sensitive skin so most times scented products irritate my skin or don’t work well with my body chemistry,” our tester shares. “As such, this deodorant was perfect for my needs. I couldn’t smell any body odor under my arms after 24 hours, even with it being unscented.”

In addition to blocking odor — even after a rigorous jumping jack warm-up and stint on the treadmill — our tester found that this deodorant, which goes on clear, works exceptionally well to minimize sweat. “I didn’t perspire as much while using this deodorant, which was nice. It's rare that roll-on deodorants with ball applicators work that well with my body, but I didn’t smell or feel sweaty at all.”

Type: Roll-on | Scent: Unscented | Lasting power: 24 hours | Antiperspirant: Yes

Best Solid

Secret Clinical Strength Invisible Deodorant

View On Amazon $13 View On Target $9 View On Walmart $13

The Secret Clinical Strength Invisible Solid is your typical smooth white stick deodorant with far-beyond-typical odor-blocking benefits. After 24 hours of wear, our tester found that their armpits still smelled lightly fragranced with no trace of body odor. “My armpits were a little damp after a brisk 15-minute walk but [it didn’t show], and the odor was controlled very well,” they share. “This is officially my all-time favorite deodorant — it has, by far, excelled my expectations.” As with all solids, if you drop it, it can crack and crumble, so be gentle with it when you’re tossing it in your gym bag or suitcase.

Type: Stick | Scent: Lavender | Lasting power: 48 hours | Antiperspirant: Yes

Best Gel

Secret Derma+ Invisible Gel Antiperspirant and Deodorant

View On Amazon $30

Prefer the texture of gel deodorants? Secret Derma+ Invisible Gel Antiperspirant and Deodorant has earned five-star accolades from over 1,800 Amazon shoppers. During our testing, we found that it applies quite wet but it dries down after a few seconds or so. “There’s no transfer at all and it smells very nice,” our reviewer says. That said, it doesn’t last for the full 24 hours it promises. “The fragrance wore off by the end of the day and you can definitely smell the sweat,” our testers says. “Still, I love how effective and affordable this deodorant is [for shorter wear] — I would recommend this product to someone who does not sweat very much.”

Type: Gel Tube | Scent: Coconut | Lasting power: 12+ hours | Antiperspirant: Yes

Best Cream

Biotherm Deo Pure Antiperspirant Cream

View On Amazon $24 View On Fragrancenet.com $21 View On Walmart $32

For a less wet, more creamy deodorant application that dries down for matte wear, check out Biotherm Antiperspirant Cream. “The deodorant went on really nicely — with the unusual dispenser, I felt like I could rub in a smaller amount without adding more to my armpit, so it fully absorbed without getting caked on,” our tester shares.

In addition to applying beautifully, this antiperspirant smells subtle and delightful. “I didn't realize this deodorant was scented until I really put my nose into my armpit — even then, I rechecked the packaging to make sure it wasn't just leftover body wash or fabric softener scent,” our tester says.

Best of all, despite being a white cream that takes a second to dry down, it doesn’t transfer at all. “I wore a dark blue shirt to the test and I didn't see any transfer — the fact that it was so easy to rub in may have helped,” our tester says.

Type: Cream Tube | Scent: Floral | Lasting power: 24 hours | Antiperspirant: Yes

Best Wipes

SweatBlock Antiperspirant Wipes

View On Amazon $20 View On Walmart $20 View On Sweatblock.com $20

Whether you travel a lot, are looking for a deodorant solution in your car or gym bag, or simply prefer the idea of a wipe over a stick, gel, or cream, SweatBlock Clinical Strength DRIBOOST Antiperspirant Wipes are worth considering. Despite being unscented, the expertly-formulated wipes prevent BO for hours on end (though, our tester did notice a musty smell around the 24-hour mark). “I stayed dry throughout my entire wear,” our tester adds. “The product appears to be a sweat reducer (the brand claims for up to seven days), and I think combined with a stick deo after day-one it would be a great pick for super sweaters.”

Type: Wipe | Scent: Unscented | Lasting power: Seven days | Antiperspirant: Yes

Best Pack

Degree Advanced Antiperspirant Deodorant

View On Amazon $20 View On Target $5 View On Walmart $9

When you find a deodorant you love, it’s only natural to want to keep a backstock. With Degree Advanced Antiperspirant Deodorant, you can do so by picking up one of the best-selling bundles of four, which have earned five-star reviews from over 8,000 Amazon shoppers. “After a full day of testing, commuting, sleeping, etc., I'm so impressed by the results,” our tester marvels. “Not only am I stink-free but my underarms also stayed dry the entire time, too. This would be an especially great product for hard workouts or marathon days.”

Type: Stick | Scent: Shower Clean | Lasting power: 72 hours | Antiperspirant: Yes

Best for Workouts

Arm & Hammer Ultra Max

View On Amazon $6 View On Walmart $7 View On IHerb

Arm & Hammer Ultra Max Deodorant is formulated with baking soda to naturally absorb odor and help prevent excess sweating — which is especially important when you’re powering through an intense workout. “This deodorant has a smooth application, great smell, and it’s an amazing bang for your buck,” our tester confirms. “I didn’t feel sweaty at all during wear, and the scent smells like laundry detergent, which I’m personally obsessed with.”

The only downside is the size of the applicator. The mouth of the stick is quite wide, which we assume is to encourage only passing it over the pit area once or twice, as the directions say to only use thin layers.

Type: Stick | Scent: Cool Blast | Lasting power: 24 hours | Antiperspirant: Yes

Best Scented

Harry's Odor & Enhanced Sweat Control, Extra-Strength Antiperspirant

View On Amazon $21 View On Target $6 View On Kohls.com $6

We cranked the workout intensity up a notch to test this stick and it held up: We didn’t stink and had less wetness than we experienced with our go-to deodorant. We had a very slight sweat smell—not odor, but that slightly salty waft. Even after a super hot day in NYC, we weren’t craving a shower (due to smell, feeling fresh is another factor) because our antiperspirant lasted.

What really wowed us were the scents. They are light, fresh, and unlike anything we had tried before. The fig one had a slight sweetness that wasn’t overly sugary. It’s not a scent we’d ever encountered but really enjoyed. And if a strong scent isn’t your thing: this one dissipated so it didn’t remain super strong throughout the day.

Type: Stick | Scent: Fresh | Lasting Power: 24 hours | Antiperspirant: Yes